ANTI-MICROBIAL EVOLUTION OF NOVEL THIAZOLES
نویسندگان
چکیده
منابع مشابه
2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation.
The present work reports on the synthesis, anti-Trypanosoma cruzi activities and docking studies of a novel series of 2-(pyridin-2-yl)-1,3-thiazoles derived from 2-pyridine thiosemicarbazone. The majority of these compounds are potent cruzain inhibitors and showed excellent inhibition on the trypomastigote form of the parasite, and the resulting structure-activity relationships are discussed. T...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical & Scientific Innovation
سال: 2014
ISSN: 2277-4572
DOI: 10.7897/2277-4572.032125